Roger Kornberg is Winzer Professor in Medicine and Professor of Structural Biology at Stanford University. He received a bachelor’s degree in chemistry from Harvard College in 1967 and a Ph.D. in chemistry from Stanford in 1972. His first research was on the dynamics of lipid bilayers. He used nuclear and electron paramagnetic resonance to determine the rates of diffusional motions of lipids, termed flip-flop and lateral diffusion. He then turned to X-ray diffraction of chromatin and, in 1974, proposed the existence and structure of the nucleosome. This proposal was borne out in detail by subsequent structural studies. Kornberg moved to his present position in 1978, where his research has focused on the mechanism and regulation of eukaryotic gene transcription. Results of this research include the near atomic structure of RNA polymerase II, the elucidation of the RNA polymerase II transcription machinery, and the discovery of the Mediator of transcriptional regulation. Parallel studies of metal clusters have included atomic structures large gold nanoparticles by X-ray crystallography and aberration-corrected electron microscopy. Kornberg has received many awards, including the Welch Prize (2001), highest award in chemistry in the United States, the Leopold Mayer Prize (2002), highest award in biomedical sciences of the French Academy of Sciences, and the Nobel Prize in Chemistry (unshared, 2006). He is a member of national academies in the US and Europe and a recipient of honorary degrees from universities in Europe and Israel. His longest and closest collaborator has been his wife, Professor Yahli Lorch. They have three children, Guy, Maya, and Gil.
Education
B.S. Chemistry, Harvard University
Ph.D. Chemistry from Stanford University
Honorary degree, Hebrew University, Jerusalem
Memberships and Fellowships
Fellow of the American Academy of Arts and Sciences
Member of EMBO
Member of the US National Academy of Sciences
Foreign Member of the Royal Society (ForMemRS)
Awards and Honors
Nobel Prize in Chemistry, 2006
Louisa Gross Horwitz Prize from Columbia University, 2006
Dickson Prize from University of Pittsburgh, 2006
General Motors Cancer Research Foundation’s Alfred P. Sloan, Jr. Prize, 2005
Massry Prize from the Keck School of Medicine, University of Southern California, 2003
Robert J. and Claire Pasarow Foundation Medical Research Award, 2003
Grand Prix Charles-Leopold Mayer, 2002
ASBMB-Merck Award, 2002
Welch Award in Chemistry, 2001
Hoppe-Seyler Award, Society for Biochemistry and Molecular Biology, Germany, 2001
Gairdner Foundation International Award, 2000
Harvey Prize from the Technion – Israel Institute of Technology, 1997
Ciba-Drew Award, 1990
Passano Award from the Passano Foundation, 1982
Eli Lilly Award in Biological Chemistry, 1981